I have sciatica and have used a number of over-the-counter products to reduce the pain. None of them provided the relief I was searching for. I found Cheech and Chong's gummies on the internet and decided to give them a try. These gummies can't cure my problem but taking two of them took the edge off and allow me to sleep through the night. I don't know if they'll work on everyone but the only way to find out is to order them and try them out. I'm a skeptic when it comes to products like but this is one product that has worked wonders on me. I've re-ordered twice. My wife even started taking them and it has helped her get to sleep.