Meder beauty is out of my budget so I'm not sure how long I'll be able to sustain the regimen but hope I can because they're so helpful. I have wrinkles and hormonal acne. My skin is sensitive and scars very easily. With constant inflammation these products have been able to compliment each other and work individually. I do wish for a SPF line. Since I have a combination of skin situations mixing and matching is a little tricky but since they're numbered and have informative descriptions it's not a complete mystery. #4 Myo-Fix Wrinkle Cream now comes smaller it appears which is a bummer. Thank you all.