I was diagnosed with Stage IV CRC (rectal, with inoperable metastasis to the liver) earlier this year, the biopsy results pointing to a MSS KRAS G12D mutation. I heard about the promising trial results with your ProBion from the following paper: Intestinal microbiota is altered in patients with colon cancer and modified by probiotic intervention. Hibberd AA, Lyra A, Ouwehand AC, et al. BMJ Open Gastro 2017;4:e000145. doi:10.1136/bmjgast-2017-000145. The description of the "1.4×1010 CFUs Bifidobacterium lactis Bl-04 and 7×109 CFUs Lactobacillus acidophilus" matches the CLINICA product so that was what I ordered. I've been taking it for about 2-3 months now. The product induced no side effects, Over that time period I've responded well to the initial round of chemo - which your product may have played a role in facilitating. So far so good.