For 30 years my Rosacea was treated with tetracycline. Then suddenly all companies stopped making it and I was stuck with nothing but to finally do some research and find out how to deal with Rosacea. So, I found out about protectiing your face from sunlight, using mild cleansers and so forth. And my research led me to Zenmed, described by consumer reports as the most effective "anti-reddening" treatment. So, that's how it all began. I noticed a difference within a few weeks, and I've been using it ever since. I use the full line of products for Rosacea, and was very happy when Zenmed introduced a line of make up. Tetracycline is back on the market, but I'm sticking with Zenmed!