i have suffered with hormonal acne since I was in my early 20's, i am now in my early 30s and have tried everything, including popular subscription skin care brands. I have never been happier with my skin since using Dr Sams. i am using most products in the range. But i think the main results are from this Radiance Duo. I have included 3 before photos in my 3 reveiw and 3 photos after 4 months of use. The results were not overnight which is expected but during my journey i havent experienced any irritation or unwanted side effects just a gentle slow progression of results.