“First time using this product so I cannot rate it long term but I have absolutely NO ill effects from it! In fact, I would say that I feel better for it but as I am not a doctor I do not want to falsely assume! It could very well be to the combined effect of the other Higher Nature products, "All Man", and "Supergar 8000"! Anyway, whatever it is, I feel better than I did before taking these products!”